Key result
Global endomyocardial and epimyocardial circumferential strain systolic peaks were significantly lower in dogs with stage C myxomatous mitral valve disease compared to stage B2 (P=0.04 and P=0.02).
Why the study?
Does two-dimensional feature tracking imaging echocardiography detect changes in myocardial deformation across different stages of myxomatous mitral valve disease in dogs?
Observational (n=48)
Does two-dimensional feature tracking imaging echocardiography detect changes in myocardial deformation across different stages of myxomatous mitral valve disease in dogs?
p-value: p=0.04 and 0.02
Two-dimensional feature tracking echocardiography can detect compensatory increases in circumferential left ventricular systolic performance due to volume overload and its subsequent loss as myxomatous mitral valve disease progresses to congestive heart failure in dogs.
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May detect deformation changes across canine MMVD stages; hypothesis-generating for feature tracking echocardiography.
Mantovani et al. (2015) conducted an observational in Myxomatous mitral valve disease (n=48). Myxomatous mitral valve disease stage C vs. Stage B2 and healthy dogs was evaluated on Global endomyocardial and epimyocardial circumferential strain systolic peak (p=0.04 and 0.02). Global endomyocardial and epimyocardial circumferential strain systolic peaks were significantly lower in dogs with stage C myxomatous mitral valve disease compared to stage B2 (P=0.04 and P=0.02).
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