Key result
Uygur centenarians exhibited a significantly higher mean 24-hour systolic blood pressure (131 vs 124 mmHg, p<0.001) and more frequent ultradian blood pressure variations compared to younger elderly subjects.
Cross-Sectional (n=133)
Absolute Event Rate: 131% vs 124%
p-value: p=<0.001
Uygur centenarians exhibit higher systolic blood pressure, more non-dipper patterns, and more frequent ultradian blood pressure variations compared to younger elderly individuals.
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Should not alter BP targets in elderly; leaves open whether ultradian patterns confer longevity benefit.
Kawamura et al. (2003) conducted a cross-sectional in Healthy elderly (n=133). Centenarian status (age ≥100 years) vs. Elderly subjects (age 65-70 years) was evaluated on Mean 24-hour systolic blood pressure (p=<0.001). Uygur centenarians exhibited a significantly higher mean 24-hour systolic blood pressure (131 vs 124 mmHg, p<0.001) and more frequent ultradian blood pressure variations compared to younger elderly subjects.
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