What's Next for Acute Heart Failure Research?
Key result
Over one million patients with acute heart failure present to a United States emergency department annually, highlighting the need for a collaborative clinical trials network to guide management.
Design
Review
Authors
Discussion
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Member takes
Implication
The high volume of acute HF ED visits warrants research infrastructure investment; leaves open optimal treatment protocols pending collaborative trials.
Key Points
- To outline research priorities and collaborative network strategies for overcoming historical stagnation in acute heart failure trial design and postdischarge outcomes.
- Convened an interdisciplinary group of emergency medicine and cardiology investigators to address trial fragmentation.
- Evaluated infrastructure requirements and enrollment barriers for executing pragmatic and explanatory acute heart failure studies.
- Established a multidisciplinary clinical trials network integrating emergency care and cardiology to resolve structural barriers in patient recruitment and care continuity.
- Identified four high-priority research targets to direct future federally funded trials and improve postdischarge event rates.
PICO
P
Population
Acute heart failure
Highlights the development of an acute heart failure clinical trials network and identifies four high-priority research areas to improve patient outcomes.
Cite This Study
Collins et al. (2017) conducted a review in Acute heart failure. Over one million patients with acute heart failure present to a United States emergency department annually, highlighting the need for a collaborative clinical trials network to guide management.