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June 1, 1972Journal of Medical GeneticsOpen Access

Incidence and genetics of Legg-Perthes disease (osteochondritis deformans) in British Columbia: evidence of polygenic determination.

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Population

Patients with Legg-Perthes disease (osteochondritis deformans) in British Columbia

Design

Other

Authors

IGIrenem . GrayUniversity of British ColumbiaRLR. Brian LowryAlberta Health ServicesDRD. H. G. RenwickAustralian Institute of Health and Welfare

Discussion

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Implication

Hypothesis-generating for polygenic Legg-Perthes etiology; should not yet alter clinical practice or counseling.

Structured PICO

P
Population
Patients with Legg-Perthes disease (osteochondritis deformans) in British Columbia
O
Outcome
Incidence and mode of inheritance of Legg-Perthes disease

This study investigates the incidence and genetic components of Legg-Perthes disease in British Columbia, suggesting polygenic determination.

Cite This Study

Gray et al. (1972) studied this question.

synapsesocial.com/papers/6a915b24fbd14437d06f2dd3https://doi.org/10.1136/jmg.9.2.197
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence of Legg–Perthes Disease (Osteochondritis Deformans)1966 · 87 citations
  2. 2Coxa Plana, Its Genetic Aspects and Results of Treatment with the Long Taylor Walking Caliper1959 · 25 citations
  3. 3Radiological Changes in Perthes' Disease1966 · 46 citations