Key result
Nonadherence with medications (OR 2.593), older age (OR 1.683), and race (OR 1.239) were significant predictors of uncontrolled systolic hypertension in patients on antihypertensive therapy.
Why the study?
What are the predictors of uncontrolled hypertension among individuals taking antihypertensive medications?
Cross-Sectional (n=2,663)
What are the predictors of uncontrolled hypertension among individuals taking antihypertensive medications?
Odds Ratio: 2.593
p-value: p=.00
Race, age, and medication nonadherence are significant predictors of uncontrolled systolic hypertension, highlighting the need for targeted interventions in older adults and African Americans.
May support adherence strategies in older adults; leaves open causal mechanisms and prospective validation.
Inadequate control of high systolic blood pressure in older adults has been largely attributable to poor control of overall hypertension (HTN). The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guidelines emphasize the importance of controlling isolated systolic HTN in older adults. The study examined demographics, self-reported health information, and clinical measures as predictors of uncontrolled HTN among individuals taking antihypertensive medications. The Community Initiative to Eliminate Stroke, a stroke risk factor screening and prevention project, collected data in two North Carolina counties. Statistical modeling of predictors included odds ratios (ORs) and logistic regression analyses. Of the 2663 participants, 43.5% and 22.8% had uncontrolled systolic and diastolic HTN, respectively. African Americans were more likely to have uncontrolled systolic (60%) or diastolic HTN (70.9%) compared with whites (40% and 29.1%, respectively). Participants 55 years and older were more likely to have uncontrolled systolic HTN compared with younger individuals. Regression analyses showed that race (OR, 1.239; P=.00), age (OR, 1.683; P=.00), and nonadherence with medications (OR, 2.593; P=.00) were significant predictors of uncontrolled systolic HTN. Future interventions should focus on improving management of isolated systolic HTN in older adults and African Americans to increase overall control of HTN.
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Dave et al. (2013) conducted a cross-sectional in Hypertension (n=2,663). Nonadherence with medications, older age, and race vs. Adherent, younger, and white participants was evaluated on Uncontrolled systolic hypertension (OR 2.593, p=.00). Nonadherence with medications (OR 2.593), older age (OR 1.683), and race (OR 1.239) were significant predictors of uncontrolled systolic hypertension in patients on antihypertensive therapy.
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