Key result
Among normolipidemic acute myocardial infarction patients, age >60 years was associated with significantly higher levels of C-reactive protein compared to age <60 years (p=0.003).
Why the study?
How do cardiovascular risk factors and inflammatory markers differ by age in normolipidemic patients presenting with acute myocardial infarction?
Case-Control (n=165)
How do cardiovascular risk factors and inflammatory markers differ by age in normolipidemic patients presenting with acute myocardial infarction?
In normolipidemic AMI patients, older age (>60 years) is associated with significantly higher CRP levels, suggesting age-related variations in inflammatory risk factors.
Answers are grounded in this paper and cite their sources.
CRP elevation in older normolipidemic AMI patients should not change practice; leaves open age-specific inflammatory mechanisms.
The goal of the present study was to address the various risk factors associated in normolipidemic acute myocardial infarction (AMI) patients admitted to the intensive coronary care unit (ICCU). The study compared serum lipid profiles, lipid peroxidation markers, antioxidants and inflammatory markers in acute myocardial infarction (AMI) patients and age/sex-matched controls. The risk variables were analysed age wise with patients 60 years of age.A lipid profile, lipid peroxidation, enzyme antioxidants, endogenous antioxidants, ischemia modified-albumin (IscMA), ceruloplasmin, C-reactive protein (CRP), fibrinogen, lipoprotein (a) and paraoxonase-1 activities were analyzed in 165 acute myocardial infarction (AMI) patients of which 45 patients were 60 years age of acute myocardial infarction patients. Higher levels of C-reactive protein (p=0.003) were observed among the >60 years age patients compared to <60 years. Other biochemical findings were not statistically significant.During the process of aging the risk factors vary as lowering of antioxidants is due to decreased free radical scavenging properties.
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A 2009 study conducted a case-control in Normolipidemic acute myocardial infarction (n=165). Age >60 years vs. Age <60 years was evaluated on C-reactive protein levels (p=0.003). Among normolipidemic acute myocardial infarction patients, age >60 years was associated with significantly higher levels of C-reactive protein compared to age <60 years (p=0.003).
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