Key result
Amiodarone treatment for refractory supraventricular tachycardia in a child was associated with the development of 2 to 1 atrioventricular conduction and QT interval prolongation.
Case Report (n=1)
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Amiodarone treatment in children can lead to toxicity manifesting as QT prolongation and 2:1 AV block, highlighting the need for careful electrocardiographic monitoring.
The potential for development of 2 to 1 atrioventricular conduction in children with prolongation of the QT interval has been previously reported secondary to electrolytic disturbances. We report here a child who developed 2 to 1 atrioventricular conduction with prolongation of the QT interval following treatment with amiodarone for refractory supraventricular tachycardia. We highlight the importance of electrocardiographic monitoring to assess for those at risk of amiodarone toxicity, which may be manifested by prolongation of the QT interval and the simultaneous loss of atrioventricular conduction, and of equal importance the need for prompt conversion to an alternative anti-arrhythmic agent.
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McMahon et al. (2003) conducted a case report in Refractory supraventricular tachycardia (n=1). Amiodarone was evaluated on 2 to 1 atrioventricular conduction with prolongation of the QT interval. Amiodarone treatment for refractory supraventricular tachycardia in a child was associated with the development of 2 to 1 atrioventricular conduction and QT interval prolongation.
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