Key result
General anesthesia combined with epidural anesthesia improved MMSE scores at 2 hours post-operation and shortened recovery times compared to general anesthesia alone in pregnant women with dystocia.
Why the study?
Does general anesthesia combined with epidural anesthesia improve postoperative cognitive recovery in pregnant women with dystocia compared to general anesthesia alone?
Cohort (n=84)
No
Does general anesthesia combined with epidural anesthesia improve postoperative cognitive recovery in pregnant women with dystocia compared to general anesthesia alone?
General anesthesia combined with epidural anesthesia improves early postoperative cognitive recovery and shortens recovery times compared to general anesthesia alone in pregnant women undergoing cesarean section for dystocia.
Answers are grounded in this paper and cite their sources.
May support combined anesthesia for faster recovery in dystocia; hypothesis-generating and requires RCT confirmation before practice change.
Effects of general anesthesia combined with epidural anesthesia on the postoperative cognitive functions in pregnant women with dystocia were investigated. Postoperative cognitive functions of 84 dystocia pregnant women treated with cesarean section were retrospectively analyzed. Patients who received general anesthesia were included in group A (n=42), and those who received general anesthesia combined with epidural anesthesia were included in group B (n=42). Mean arterial pressure (MAP), heart rate (HR) and bispectral index (BIS) at different time-points after anesthesia in the two groups of patients were observed and compared. Recovery of anesthesia such as the recovery time of spontaneous breathing, recovery time of orientation and time of eye opening were observed and compared between two groups of patients. Mini mental state examination (MMSE) scores were obtained and compared between the the groups of patients at different time-points after operation. Three vital signs (MAP, HR and BIS) were not significantly different between group A and B at the same time-point (P>0.05) and the maintenance of anesthesia was satisfactory. Compared with group A, postoperative recovery time of spontaneous breathing, recovery time of orientation and the time of eye opening in group B were all significantly shorter (P<0.05). In addition, MMSE scores of patients in group B, 2 and 12 h after operation were 24.33±1.61 and 26.41±1.83 points, respectively, which were significantly improved compared with those of patients in group A (20.45±1.58 and 22.39±1.72 points, respectively) (P<0.05). In conclusion, recovery of postoperative cognitive functions in pregnant women with dystocia who received general anesthesia combined with epidural anesthesia was shorter to that of those who only received general anesthesia.
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Fu et al. (2018) conducted a cohort in Dystocia in pregnant women requiring cesarean section (n=84). General anesthesia combined with epidural anesthesia vs. General anesthesia alone was evaluated on Mini mental state examination (MMSE) score at 2 hours post-operation (p=0.036). General anesthesia combined with epidural anesthesia improved MMSE scores at 2 hours post-operation and shortened recovery times compared to general anesthesia alone in pregnant women with dystocia.
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