Why the study?
Do plasma ANP concentrations differ in patients with SIADH or central DI compared to normal subjects?
Population
15 patients with the syndrome of inappropriate antidiuretic hormone secretion and 17 patients with central…
Comparison
Measurement of plasma ANP concentrations before… vs Normal subjects
Design
Cross-sectional
Authors
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Altered ANP levels in SIADH and DI support volume homeostasis role; cross-sectional data leave open diagnostic or therapeutic utility.
Do plasma ANP concentrations differ in patients with SIADH or central DI compared to normal subjects?
ANP secretion is modulated by changes in plasma volume consequent to abnormal AVP secretion, suggesting a pathophysiological role in maintaining volume homeostasis.
Kamoi et al. (1990) studied this question.
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