Key result
Plasma BNP levels were significantly higher in hypertensive patients compared to cycling athletes and controls, despite athletes having significantly larger left ventricular mass index.
Why the study?
Are B-type natriuretic peptide (BNP) levels elevated in athletes with physiologically increased left ventricular mass compared to hypertensive patients with pathologically increased left ventricular mass?
Population
40 subjects including 8 cycling athletes, 8 healthy age-matched controls, 17 hypertensive patients, and 7…
Design
Cross-sectional
Authors
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Supports BNP to differentiate pathological from physiological LVH; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=40)
Are B-type natriuretic peptide (BNP) levels elevated in athletes with physiologically increased left ventricular mass compared to hypertensive patients with pathologically increased left ventricular mass?
BNP levels are elevated in pathological left ventricular hypertrophy due to hypertension but not in physiological hypertrophy seen in athletes.
Almeida et al. (2002) conducted a cross-sectional in Hypertension and physiological left ventricular hypertrophy (n=40). Hypertension and athletic training vs. Healthy age-matched controls was evaluated on Plasma levels of BNP and left ventricular mass index (LVMI). Plasma BNP levels were significantly higher in hypertensive patients compared to cycling athletes and controls, despite athletes having significantly larger left ventricular mass index.
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