Key result
A plasma BNP cut-off point of 25 pg/ml was optimal for detecting left ventricular diastolic dysfunction and hypertrophy during mass screening of office workers.
Why the study?
Does plasma BNP measurement accurately detect asymptomatic left ventricular dysfunction and hypertrophy in a general screening population?
Population
818 office workers who participated in a 1996 routine health check at Kansai University.
Design
Cross-sectional
Authors
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May support 25 pg/ml BNP threshold for office worker screening; leaves open need for prospective validation before broader adoption.
Cross-Sectional (n=818)
No
Does plasma BNP measurement accurately detect asymptomatic left ventricular dysfunction and hypertrophy in a general screening population?
A BNP cut-off of 25 pg/ml is a useful diagnostic marker for detecting asymptomatic left ventricular diastolic dysfunction and hypertrophy during routine health screening.
Iida et al. (2000) conducted a cross-sectional in Left ventricular dysfunction (n=818). Plasma BNP measurement was evaluated on Detection of LV diastolic dysfunction and LV hypertrophy. A plasma BNP cut-off point of 25 pg/ml was optimal for detecting left ventricular diastolic dysfunction and hypertrophy during mass screening of office workers.
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