Key result
Plasma concentration of BNP was positively correlated with LVEDD and LVESD and inversely correlated with LVEF, indicating it is a sensitive marker of impaired left-ventricular function.
Why the study?
Does plasma BNP concentration correlate with echocardiographic indicators of left-ventricular dysfunction in elderly patients with cardiovascular disease?
Population
Elderly patients with various cardiovascular diseases, including prior myocardial infarction, dilated…
Comparison
Measurement of plasma brain natriuretic peptide… vs Echocardiographic parameters as reference standard
Design
Cohort
Authors
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May support BNP for LV monitoring in elderly CVD; hypothesis-generating, needs prospective validation before guiding therapy.
Observational
Does plasma BNP concentration correlate with echocardiographic indicators of left-ventricular dysfunction in elderly patients with cardiovascular disease?
Plasma BNP is a sensitive marker of impaired left-ventricular function and may be useful for evaluating therapeutic efficacy in elderly patients with congestive heart failure.
Yamada et al. (2008) conducted an observational in Cardiovascular disease. Plasma concentration of brain natriuretic peptide (BNP) was evaluated on Correlation with echocardiographic findings (LVEDD, LVESD, LVEF). Plasma concentration of BNP was positively correlated with LVEDD and LVESD and inversely correlated with LVEF, indicating it is a sensitive marker of impaired left-ventricular function.
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