January 1, 1990Echocardiography

Successful Opacification of the Left Heart Chambers on Echocardiographic Examination after Intravenous Injection of a New Saccharide Based Contrast Agent

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Why the study?

Does intravenous injection of the contrast agent SH U 508 provide diagnostic left heart opacification in healthy volunteers?

Population

5 healthy male volunteers

Design

Case_series

Authors

RSReinhard SchliefPhysikalisch-Technische Bundesanstalt TST StaksBayer (Germany)MMMarianne MahlerAalborg University

Discussion

Member takes

Implication

May support SH U 508 for left heart contrast echo; leaves open validation in patients.

Structured PICO

Does intravenous injection of the contrast agent SH U 508 provide diagnostic left heart opacification in healthy volunteers?

Population

5 healthy male volunteers

Intervention

Intravenous injection of a new monosaccharide microparticle based echocardiographic contrast agent (SH U 508) in incremental volumes (2, 4, 8, and 16 mL) and concentrations (50, 100, 200, 300, and 400 mg/mL)

Outcome

Left heart opacification of diagnostic valuesurrogate

The novel saccharide-based contrast agent SH U 508 safely provides diagnostic opacification of the left heart chambers during echocardiography.

Cite This Study

Schlief et al. (1990) studied this question.

synapsesocial.com/papers/6a9180d1e771dc7bc33407e6 https://doi.org/10.1111/j.1540-8175.1990.tb00349.x

Topics

Echocardiography

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