Key result
Physical activity modified genetic effects on blood pressure, with active individuals showing reductions in SBP and DBP up to 8 and 5 mm Hg compared to inactive individuals with the same genotypes.
Why the study?
Does physical activity modify the association between genetic variants and blood pressure in rural Chinese villagers?
Population
3,142 rural Chinese villagers
Comparison
Physical activity and genetic variants vs Physical inactivity (physically inactive group)
Design
Cross-sectional
Authors
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Physical activity may lower BP across genotypes; hypothesis-generating from cross-sectional data, needing prospective confirmation.
Observational (n=3,142)
Does physical activity modify the association between genetic variants and blood pressure in rural Chinese villagers?
Effect estimate: reductions of SBP and DBP as large as 8 and 5 mm Hg
Physical activity modifies the effects of genetic variants on blood pressure, with active individuals consistently having lower blood pressure than inactive individuals with the same genotypes.
Montasser et al. (2011) conducted an observational in Blood pressure (n=3,142). Physical activity vs. Physical inactivity was evaluated on Systolic blood pressure (SBP) and diastolic blood pressure (DBP) (reductions of SBP and DBP as large as 8 and 5 mm Hg). Physical activity modified genetic effects on blood pressure, with active individuals showing reductions in SBP and DBP up to 8 and 5 mm Hg compared to inactive individuals with the same genotypes.
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