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October 13, 1951JAMA

Agranulocytosis Following Maintenance Dosage of Pronestyl

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Population

1 patient, 87-year-old woman with cardiac failure, acute pulmonary edema, and ventricular arrhythmia.

Design

Case_report

Follow-up

8 weeks

Authors

MIMiyoko Inouye

Discussion

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Implication

Alerts clinicians to agranulocytosis risk on procainamide maintenance; leaves open incidence quantification in broader populations.

Structured PICO

P
Population
1 patient, 87-year-old woman with cardiac failure, acute pulmonary edema, and ventricular arrhythmia.
I
Intervention
Procaine amide hydrochloride (pronestyl) maintenance dosage over 8 weeks
O
Outcome
Agranulocytosissafety

This case report highlights the risk of agranulocytosis associated with maintenance therapy of procaine amide hydrochloride.

Cite This Study

Miyoko Inouye (1951) studied this question.

synapsesocial.com/papers/6a918471ca59a4cbdea16c52https://doi.org/10.1001/jama.1951.73670240016006g
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE ACTION OF PROCAINE AMIDE IN CARDIAC ARRHYTHMIAS1951 · 31 citations
  2. 2THE CONTROL OF THE HEART BEAT BY THE SURGEON1937 · 76 citations
  3. 3Sympatholytic Effects of Diethylaminoethanol in Man.1949 · 2 citations