Key result
Continuous noninvasive arterial pressure monitoring showed good agreement with invasive monitoring for mean arterial pressure (bias 0.039 mmHg; limits of agreement -5.95 to 6.03 mmHg).
Why the study?
Does a continuous noninvasive arterial blood pressure (CNAP) monitor provide comparable real-time estimates of arterial pressure to an invasive arterial catheter in cardiac surgical ICU patients?
Observational (n=30)
Does a continuous noninvasive arterial blood pressure (CNAP) monitor provide comparable real-time estimates of arterial pressure to an invasive arterial catheter in cardiac surgical ICU patients?
Mean Difference: 0.03944
The CNAP monitor provides reliable, real-time estimates of arterial pressure comparable to invasive arterial catheters in cardiac surgical ICU patients.
Supports CNAP for MAP monitoring in cardiac surgical ICU; hypothesis-generating pending randomized validation.
Accurate measurement and display of arterial blood pressure is essential for rational management of adult cardiac surgical patients. Because of the lower risk of complications, noninvasive monitoring methods gain importance. A newly developed continuous noninvasive arterial blood pressure (CNAP™) monitor is available and has been validated perioperatively. In a prospective study we compared the CNAP™ monitoring device with invasive arterial blood pressure (IAP) measurement in 30 patients in a cardiac surgical Intensive Care Unit (ICU). Patients were either mechanically ventilated or spontaneously breathing, with or without inotropes. CNAP™ was applied on two fingers of the hand contralateral to the IAP monitoring catheter. Systolic, diastolic and mean pressure data were recorded every minute for 2 h simultaneously for both IAP and CNAP™. Statistical analysis included construction of mountain plot and Bland Altman plots for assessing limits of agreement and bias (accuracy) calculation. Three thousand and six hundred pairs of data were analyzed. The CNAP™ systolic arterial pressure bias was 10.415 mmHg and the CNAP™ diastolic arterial pressure bias was -5.3386 mmHg; the mean arterial pressure (MAP) of CNAP™ was close to the MAP of IAP, with a bias of 0.03944 mmHg. The Bland Altman plot showed a uniform distribution and a good agreement of all arterial blood pressure values between CNAP™ and IAP. Percentage within limits of agreement was 94.5%, 95.1% and 99.4% for systolic, diastolic and MAP. Calculated limits of agreement were -4.60 to 25.43, -13.38 to 2.70 and -5.95 to 6.03 mmHg for systolic, diastolic and mean BP, respectively. The mountain plot showed similar results as the Bland Altman plots. We conclude CNAP™ is a reliable, noninvasive, continuous blood pressure monitor that provides real-time estimates of arterial pressure comparable to those generated by an invasive arterial catheter system. CNAP™ can be used as an alternative to IAP.
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Singh et al. (2012) conducted an observational in cardiac surgical ICU patients (n=30). Continuous noninvasive arterial pressure (CNAP™) monitor vs. Invasive arterial blood pressure (IAP) measurement was evaluated on Agreement and bias for systolic, diastolic and mean arterial pressure (bias 0.03944 mmHg (MAP)). Continuous noninvasive arterial pressure monitoring showed good agreement with invasive monitoring for mean arterial pressure (bias 0.039 mmHg; limits of agreement -5.95 to 6.03 mmHg).
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