December 1, 1960Circulation

Spontaneous Closure of Ventricular Septal Defects

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Population

37 children with clinical findings suggesting a small ventricular septal defect.

Design

Case_series

Authors

JEJohn R. EvansSwinburne University of Technology RRRichard D. RoweWomen & Children's Hospital of Buffalo JKJohn D. KeithUniversity of Alabama at Birmingham

Discussion

Member takes

Implication

May support observation for small VSDs; hypothesis-generating for rare spontaneous closure in large symptomatic lesions.

Structured PICO

Population

37 children with clinical findings suggesting a small ventricular septal defect (systolic murmur heard early in life that gradually diminished and eventually disappeared).

Outcome

Spontaneous closure of the ventricular septal defect (disappearance of systolic murmur and normalization of hemodynamic findings).

Small muscular ventricular septal defects in children can spontaneously close over time, likely due to hypertrophy of septal muscle.

Cite This Study

Evans et al. (1960) studied this question.

synapsesocial.com/papers/6a918fdc87dfe5d232f143bc https://doi.org/10.1161/01.cir.22.6.1044

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Spontaneous Closure of Ventricular Septal Defects

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Spontaneous Closure of Ventricular Septal Defects

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider