Key result
In patients with type 2 diabetes, albuminuria was an independent predictor for increased arterial stiffness, specifically showing a positive correlation with the cardio-ankle vascular index (CAVI).
Cross-Sectional (n=106)
No
Effect estimate: r = 0.285
p-value: p=0.003
Background: Brachial ankle pulse wave velocity (BaPWV) and cardio ankle vascular index (CAVI), as indicators of arterial stiffness, are increased in type 2 diabetes. Albuminuria, as a cardiovascular risk factor in type 2 diabetes, can cause endothelial dysfunction and atherosclerosis, and these can increase arterial stiffness. So we investigated the hypothesis that increased albuminuria reflects increased BaPWV and CAVI in type 2 diabetes.
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Lee et al. (2007) conducted a cross-sectional in Type 2 Diabetes (n=106). Albuminuria (Urine albumin creatinine ratio) vs. Normal albuminuria was evaluated on Cardio-ankle vascular index (CAVI) (r = 0.285, p=0.003). In patients with type 2 diabetes, albuminuria was an independent predictor for increased arterial stiffness, specifically showing a positive correlation with the cardio-ankle vascular index (CAVI).
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