What does this research mean for the field?

Elevated brachial-ankle pulse wave velocity (baPWV) is independently associated with 66% higher odds of albuminuria in a Chinese adult population. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study investigates the relationship between albuminuria and arterial stiffness in a Chinese population.

March 1, 2026MedicineOpen Access

Association between albuminuria and arterial stiffness measured by brachial-ankle pulse wave velocity among Chinese population: A retrospective study

Q: What are the key findings of this study?

Elevated baPWV is independently associated with 66% higher odds of albuminuria (adjusted OR 1.66, 95% CI: 1.18–2.33) in a Chinese adult population.

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Key result

Elevated baPWV is linked to ~66% higher odds of albuminuria.

OR 1.66
95% CI: 1.18–2.33

Why the study?

Albuminuria and arterial stiffness may be interconnected through shared pathophysiological mechanisms, but their association required evaluation in a Chinese health checkup population.

Is elevated arterial stiffness associated with increased odds of albuminuria in a health checkup population?

Population

5025 adults undergoing health examinations between 2013 and 2014 in China

Comparison

Elevated baPWV (baPWV ≥1400 cm/s) vs normal baPWV

Design

Retrospective study

Authors

WYWei-Chung YehKeelung Chang Gung Memorial Hospital WLWen-Cheng LiChang Gung University MWMei-Wen WangTongji University

Discussion

Member takes

Implication

May prompt renal screening with elevated arterial stiffness; hypothesis-generating and requires prospective studies to establish causality.

Key Points

This study investigates the relationship between albuminuria and arterial stiffness in a Chinese population.
Retrospective analysis of data from 5025 adults during 2013-2014 health checkups.
Defined albuminuria as an albumin-to-creatinine ratio ≥30 mg/g.
Measured arterial stiffness through brachial-ankle pulse wave velocity (baPWV) ≥1400 cm/s.
Utilized logistic regression models to adjust for confounders such as age, sex, and metabolic indicators.
Participants with albuminuria showed higher body mass index, waist circumference, blood pressure, triglycerides, fasting plasma glucose, and baPWV.
Elevated baPWV was associated with increased odds of albuminuria with an adjusted odds ratio of 1.66.
Significant predictors of albuminuria included waist-to-height ratio, mean arterial pressure, and fasting glucose.

Structured PICO

Is elevated arterial stiffness associated with increased odds of albuminuria in a health checkup population?

Population

5,025 adults from a Chinese health checkup population who underwent health examinations between 2013 and 2014

Intervention

Elevated arterial stiffness (brachial-ankle pulse wave velocity [baPWV] ≥1400 cm/s)

Comparator

Normal arterial stiffness (baPWV <1400 cm/s)

Outcome

Albuminuria (defined as albumin-to-creatinine ratio ≥30 mg/g)surrogate

Elevated arterial stiffness, measured by baPWV, is independently associated with the presence of albuminuria in Chinese adults.

Cite This Study

Yeh et al. (2026) studied this question. Elevated baPWV is independently associated with 66% higher odds of albuminuria (adjusted OR 1.66, 95% CI: 1.18–2.33) in a Chinese adult population.

synapsesocial.com/papers/69a3d8a7ec16d51705d2fb28 https://doi.org/10.1097/md.0000000000047855

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March 1, 2026MedicineOpen Access

Association between albuminuria and arterial stiffness measured by brachial-ankle pulse wave velocity among Chinese population: A retrospective study

View Full Paper

Ask AI

Bookmark

Key result

Elevated baPWV is linked to ~66% higher odds of albuminuria.

OR 1.66
95% CI: 1.18–2.33

Why the study?

Albuminuria and arterial stiffness may be interconnected through shared pathophysiological mechanisms, but their association required evaluation in a Chinese health checkup population.

Is elevated arterial stiffness associated with increased odds of albuminuria in a health checkup population?

Population

5025 adults undergoing health examinations between 2013 and 2014 in China

Comparison

Elevated baPWV (baPWV ≥1400 cm/s) vs normal baPWV

Design

Retrospective study

Authors

WYWei-Chung YehKeelung Chang Gung Memorial Hospital WLWen-Cheng LiChang Gung University MWMei-Wen WangTongji University

Discussion

Member takes

Implication

May prompt renal screening with elevated arterial stiffness; hypothesis-generating and requires prospective studies to establish causality.

Key Points

This study investigates the relationship between albuminuria and arterial stiffness in a Chinese population.
Retrospective analysis of data from 5025 adults during 2013-2014 health checkups.
Defined albuminuria as an albumin-to-creatinine ratio ≥30 mg/g.
Measured arterial stiffness through brachial-ankle pulse wave velocity (baPWV) ≥1400 cm/s.
Utilized logistic regression models to adjust for confounders such as age, sex, and metabolic indicators.
Participants with albuminuria showed higher body mass index, waist circumference, blood pressure, triglycerides, fasting plasma glucose, and baPWV.
Elevated baPWV was associated with increased odds of albuminuria with an adjusted odds ratio of 1.66.
Significant predictors of albuminuria included waist-to-height ratio, mean arterial pressure, and fasting glucose.

Structured PICO

Is elevated arterial stiffness associated with increased odds of albuminuria in a health checkup population?

Population

5,025 adults from a Chinese health checkup population who underwent health examinations between 2013 and 2014

Intervention

Elevated arterial stiffness (brachial-ankle pulse wave velocity [baPWV] ≥1400 cm/s)

Comparator

Normal arterial stiffness (baPWV <1400 cm/s)

Outcome

Albuminuria (defined as albumin-to-creatinine ratio ≥30 mg/g)surrogate

Elevated arterial stiffness, measured by baPWV, is independently associated with the presence of albuminuria in Chinese adults.

Cite This Study

Yeh et al. (2026) studied this question. Elevated baPWV is independently associated with 66% higher odds of albuminuria (adjusted OR 1.66, 95% CI: 1.18–2.33) in a Chinese adult population.

synapsesocial.com/papers/69a3d8a7ec16d51705d2fb28 https://doi.org/10.1097/md.0000000000047855

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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