Key result
Microalbuminuria was independently associated with higher brachial-ankle pulse wave velocity (P=0.002), but not with 24-hour ambulatory blood pressure or carotid intima-media thickness.
Why the study?
Is microalbuminuria associated with increased brachial-ankle pulse wave velocity, carotid intima-media thickness, or ambulatory blood pressure in the general population?
Population
328 individuals from the general population of Ohasama, a rural Japanese community, mean age 65.7 +/- 6.4…
Comparison
Microalbuminuria vs Normoalbuminuria
Design
Cross-sectional
Authors
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Suggests microalbuminuria reflects arterial stiffness beyond BP; hypothesis-generating, needs prospective validation before risk stratification use.
Cross-Sectional (n=328)
No
Is microalbuminuria associated with increased brachial-ankle pulse wave velocity, carotid intima-media thickness, or ambulatory blood pressure in the general population?
p-value: p=0.002
Microalbuminuria is independently associated with increased brachial-ankle pulse wave velocity, suggesting a close link with arterial stiffness beyond blood pressure.
Ishikawa et al. (2008) conducted a cross-sectional in General population (n=328). Microalbuminuria vs. Normoalbuminuria was evaluated on Independent association with brachial-ankle pulse wave velocity (baPWV) (p=0.002). Microalbuminuria was independently associated with higher brachial-ankle pulse wave velocity (P=0.002), but not with 24-hour ambulatory blood pressure or carotid intima-media thickness.
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