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January 1, 2006Hypertension ResearchOpen Access

Brachial-Ankle Pulse Wave Velocity Is an Independent Risk Factor for Microalbuminuria in Patients with Essential Hypertension-A Japanese Trial on the Prognostic Implication of Pulse Wave Velocity (J-TOPP)

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Why the study?

Is higher brachial-ankle pulse wave velocity associated with a greater risk of microalbuminuria in never-treated hypertensive patients?

Population

718 never-treated hypertensive patients registered in a prospective study

Comparison

Higher brachial-ankle pulse wave velocity vs Lower brachial-ankle pulse wave velocity

Design

Cohort

Authors

MMMasanori MunakataTNT NunokawaKYKAORU YOSHINAGA

Discussion

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Overview

Higher brachial-ankle pulse wave velocity was associated with microalbuminuria; leaves open its incremental value for risk stratification in hypertension.

Structured PICO

Is higher brachial-ankle pulse wave velocity associated with a greater risk of microalbuminuria in never-treated hypertensive patients?

P
Population
718 never-treated hypertensive patients registered in a prospective study
I
Intervention
Higher brachial-ankle pulse wave velocity
C
Comparator
Lower brachial-ankle pulse wave velocity
O
Outcome
Microalbuminuriasurrogate

Brachial-ankle pulse wave velocity is an independent risk factor for microalbuminuria in never-treated hypertensive patients, suggesting its utility as a marker for early vascular damage.

Cite This Study

Munakata et al. (2006) studied this question.

synapsesocial.com/papers/6a87f72b4c82be800eeb3311https://doi.org/10.1291/hypres.29.515
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Higher brachial-ankle pulse wave velocity as an independent risk factor for future microalbuminuria in patients with essential hypertension: the J-TOPP study2009 · 51 citations
  2. 2Association of Microalbuminuria With Brachial-Ankle Pulse Wave Velocity: The Ohasama Study2008 · 43 citations
  3. 3Brachial-Ankle Pulse Wave Velocity and Microalbuminuria2006 · 3 citations
  4. 4Association between albuminuria and arterial stiffness measured by brachial-ankle pulse wave velocity among Chinese population: A retrospective study2026
  5. 5Elevated Brachial-Ankle Pulse Wave Velocity Is Independently Associated with Microalbuminuria in a Rural Population2014 · 11 citations