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June 18, 2009Journal of Hypertension

Higher brachial-ankle pulse wave velocity as an independent risk factor for future microalbuminuria in patients with essential hypertension: the J-TOPP study

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Why the study?

Does higher brachial-ankle pulse wave velocity predict future microalbuminuria in nondiabetic patients with essential hypertension?

Population

321 nondiabetic patients with essential hypertension who had normoalbuminuria or microalbuminuria and were…

Design

Cohort

Follow-up

2 years

Authors

MMMasanori MunakataTohoku Rosai HospitalYMYukio MiuraApple (Israel)KYKAORU YOSHINAGATokushima University

Discussion

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Implication

May support baPWV for microalbuminuria risk stratification in treated hypertension; leaves open whether arterial stiffness interventions alter renal outcomes.

Structured PICO

Does higher brachial-ankle pulse wave velocity predict future microalbuminuria in nondiabetic patients with essential hypertension?

P
Population
321 nondiabetic patients with essential hypertension who had normoalbuminuria or microalbuminuria and were receiving treatment under the current hypertension guidelines
I
Intervention
Measurement of brachial-ankle pulse wave velocity (baPWV)
O
Outcome
Microalbuminuria status at 2 yearssurrogate

Higher brachial-ankle pulse wave velocity is an independent predictor of future microalbuminuria in nondiabetic patients with essential hypertension.

Cite This Study

Munakata et al. (2009) studied this question.

synapsesocial.com/papers/6a1fc7e9ce3cb5ba46e69a29https://doi.org/10.1097/hjh.0b013e32832b4740

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors Related to the Occurrence of Microalbuminuria During Antihypertensive Treatment in Essential Hypertension2002 · 50 citations
  2. 2Brachial-Ankle Pulse Wave Velocity Is an Independent Risk Factor for Microalbuminuria in Patients with Essential Hypertension-A Japanese Trial on the Prognostic Implication of Pulse Wave Velocity (J-TOPP)2006 · 48 citations
  3. 3The Predictive Value of Brachial-Ankle Pulse Wave Velocity in Coronary Atherosclerosis and Peripheral Artery Diseases in Urban Chinese Patients2008 · 69 citations
  4. 4Determinants of urinary albumin excretion reduction in essential hypertension: a long-term follow-up study2006 · 29 citations
  5. 5Validity, Reproducibility, and Clinical Significance of Noninvasive Brachial-Ankle Pulse Wave Velocity Measurement.2002 · 1,633 citations