Key result
The T allele of the CRLR gene SNP rs696574 was significantly more frequent in women with essential hypertension compared to normotensive women (P = .032).
Why the study?
Is there an association between single-nucleotide polymorphisms in the human CRLR gene and essential hypertension in a Japanese population?
Population
425 individuals from a Japanese population, comprising 209 patients with essential hypertension and 216…
Comparison
Assessment of four single-nucleotide… vs Normotensive individuals
Design
Case-control
Authors
Loading...
Should not yet change hypertension risk assessment in women; leaves open whether CRLR rs696574 is a replicable marker.
Case-Control (n=425)
Is there an association between single-nucleotide polymorphisms in the human CRLR gene and essential hypertension in a Japanese population?
p-value: p=0.032
The SNP rs696574 in the CRLR gene may serve as a genetic marker for essential hypertension in Japanese women.
Sano et al. (2005) conducted a case-control in essential hypertension (n=425). CRLR gene single-nucleotide polymorphisms vs. Normotensive individuals was evaluated on Distribution of genotypes or alleles of CRLR gene SNPs (p=0.032). The T allele of the CRLR gene SNP rs696574 was significantly more frequent in women with essential hypertension compared to normotensive women (P = .032).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: