Why the study?
Do computer-assisted dosage regimens reduce the frequency of adverse reactions in patients receiving digitalis glycosides?
Population
Patients receiving digitalis glycosides, including those with renal disease or uncertain states of…
Comparison
Computer-assisted dosage regimens of digitalis… vs Standard or historical dosage regimens
Design
Cohort
Authors
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May reduce glycoside adverse reactions with computer-assisted dosing; hypothesis-generating and should not yet change practice.
Do computer-assisted dosage regimens reduce the frequency of adverse reactions in patients receiving digitalis glycosides?
Computer-assisted dosage regimens for digitalis glycosides significantly reduce the frequency of adverse reactions by individualizing dosing based on pharmacokinetics, body weight, and renal function.
Roger W. Jelliffe (1972) studied this question.
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