Why the study?
Does metoprolol combined with diazepam reduce pre-operative anxiety in patients undergoing elective surgery?
Population
n=98 patients undergoing elective hysterectomy or orthopaedic surgery
Comparison
Metoprolol combined with diazepam given 1-3… vs Placebo combined with diazepam given 1-3 hours…
Design
RCT, double-blind
Follow-up
1-3 hours (before induction of anaesthesia)
Authors
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Supports metoprolol addition to diazepam premedication for elective surgery; confirms anxiolytic benefit in RCT.
Does metoprolol combined with diazepam reduce pre-operative anxiety in patients undergoing elective surgery?
The addition of metoprolol to diazepam premedication significantly reduces pre-operative anxiety and improves sedation in patients undergoing elective surgery.
Jakobsen et al. (1990) studied this question.
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