Key result
Intravenous diazepam reduced preoperative anxiety in highly anxious young female patients to the level of less anxious patients, and normalized thiopental sodium induction requirements.
Why the study?
Does intravenous diazepam reduce preoperative anxiety in young female patients about to undergo operation?
Population
Young female patients about to undergo operation
Comparison
Intravenous diazepam vs Placebo
Design
Other, double-blind
Authors
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May support targeted preoperative use in highly anxious young women; leaves open generalizability and causality.
RCT
Double-blind
Does intravenous diazepam reduce preoperative anxiety in young female patients about to undergo operation?
Intravenous diazepam effectively reduces preoperative anxiety and the subsequent requirement for induction anesthesia in highly anxious young female surgical patients.
Williams et al. (1975) conducted an RCT in Preoperative anxiety. Intravenous diazepam vs. Placebo was evaluated on Preoperative anxiety measured by the Skin Conductance Anxiety Test (SCAT). Intravenous diazepam reduced preoperative anxiety in highly anxious young female patients to the level of less anxious patients, and normalized thiopental sodium induction requirements.
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