Why the study?
Does nifedipine and/or methylprednisolone reduce leucocyte elastase release in adult patients undergoing cardiopulmonary bypass?
Does nifedipine and/or methylprednisolone reduce leucocyte elastase release in adult patients undergoing cardiopulmonary bypass?
Nifedipine and methylprednisolone do not significantly inhibit the moderate leucocyte elastase release associated with cardiopulmonary bypass.
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Nifedipine and methylprednisolone were not associated with reduced elastase release; leaves open whether bypass duration drives neutrophil activation in CPB.
Massaut et al. (1991) studied this question.
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