Why the study?
The prognostic value of the PET tracer [68Ga]-NODAGA-RGD for functional outcome and cardiac remodeling remained unclear.
In a murine MI model, [68Ga]-NODAGA-RGD PET successfully imaged angiogenesis, but the extent of angiogenesis did not predict functional improvement following cardiac stem cell therapy.
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Establishes [68Ga]-NODAGA-RGD PET in murine post-MI model; leaves open its prognostic value for remodeling in patients.
Lang et al. (2020) studied this question.
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