Why the study?
What are the hemodynamic mechanisms underlying hypotension during hemodialysis in susceptible patients?
Population
21 hemodialysis patients with a high incidence of hypotension
Comparison
Combined dialysis/ultrafiltration and lower body… vs Comparison between patients who became…
Design
Cohort
Authors
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Impaired vasoconstriction may underlie intradialytic hypotension; hypothesis-generating for vascular-targeted interventions pending prospective confirmation.
What are the hemodynamic mechanisms underlying hypotension during hemodialysis in susceptible patients?
Dialysis-related hypotension appears to result from an inability to adequately increase arteriolar tone and a reduction in left ventricular function, rather than an inability to maintain blood volume.
Nette et al. (2005) studied this question.
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