Why the study?
Does abolition of the renin-angiotensin system alter vascular conductance responses to sympathetic nerve stimulation and norepinephrine in rabbits?
Population
Anesthetized rabbits
Comparison
Bilateral nephrectomy or chronic ACE inhibition… vs Normal control rabbits
Design
Preclinical
Follow-up
Up to 5 days
Authors
Loading...
Should not change RAS or sympathetic management in patients; leaves open whether angiotensin potentiates sympathetic vascular responses in humans.
Does abolition of the renin-angiotensin system alter vascular conductance responses to sympathetic nerve stimulation and norepinephrine in rabbits?
The renin-angiotensin system potentiates the effect of sympathetic nerve stimulation on vascular conductance, indicating a long-term physiological role in blood pressure control.
Randall et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: