Why the study?
Do automated and triplicate blood pressure measurements reduce variability and required sample size compared to manual and single measurements in healthy volunteers?
Do automated and triplicate blood pressure measurements reduce variability and required sample size compared to manual and single measurements in healthy volunteers?
Collecting blood pressure in triplicate rather than a single measurement significantly reduces the required sample size for detecting small blood pressure changes in early-phase clinical trials.
Authors
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Triplicate BP assessment may optimize early-phase trial efficiency; extends methodological standards for minimizing variability in SBP measurements.
Terra et al. (2004) studied this question.
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