Population
Mouse muscle cell lines (C3H10T1/2, C2C12, BC3H-1, and derived Aza, TD, TG, BD cell lines)
Comparison
5-azacytidine treatment or stable transfection… vs Parental/unconverted cell lines
Design
Preclinical
Authors
Loading...
Decouples MHC isoform expression from MyoD1/myogenin in cell lines; leaves open upstream regulators of myogenic differentiation.
In mouse muscle cell lines, the expression pattern of myosin heavy chain isoforms does not correlate with the expression patterns of the myogenic regulatory factors MyoD1 and myogenin.
Jeffrey B. Miller (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: