Why the study?
Does quantitative MRI reveal gender-specific patterns of muscle pathology in patients with limb-girdle muscular dystrophy 2I?
Population
38 adult ambulant patients with limb-girdle muscular dystrophy 2I with genetically identical mutations in…
Design
Cross-sectional
Authors
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Suggests sex-specific MRI patterns in LGMD2I merit consideration; leaves open validation and outcome prediction in prospective studies.
Does quantitative MRI reveal gender-specific patterns of muscle pathology in patients with limb-girdle muscular dystrophy 2I?
Quantitative Dixon MRI serves as an objective marker of disease and reveals previously unreported gender-specific patterns of muscle involvement in LGMD2I.
Willis et al. (2014) studied this question.
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