Why the study?
The study was conducted to evaluate the ultrastructure of the left atrial appendage endocardium in patients with atrial fibrillation as a prerequisite for local embologenic thrombus formation.
Long-standing persistent atrial fibrillation is associated with irreversible structural degradation of the left atrial appendage endocardium, providing a pathophysiological basis for local thrombus formation.
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Сотников et al. (2021) studied this question.
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