The feeding of restricted roughage with high levels of concentrates produced significant declines in milk fat in lactating cows and goats. Associated with the decline in milk fat were a signficant increase in the concentration of tureen propionie acid and a deeremse in blood ketone bodies. There was a decrease in arterial-blood acetic acid and in the arterial-nmmmary difference under conditions of ground and restricted-roughage feeding. The feeding of sodium acetate tended to increase low milk fat, and the feeding of sodium propionate tended to lower it further. An hypothesis regarding a mechanism of milk-fat depression based on the antiketogenic properties of propionic acid is discussed.
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Soest et al. (1959) studied this question.
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