Key result
Hyperinsulinemic hypoglycemia reduced NO-mediated endothelial vasodilation and increased proatherothrombotic mechanisms compared with euglycemia in healthy individuals.
Why the study?
Does hyperinsulinemic hypoglycemia impair vascular function and increase proatherothrombotic mechanisms in healthy individuals?
Population
healthy individuals
Comparison
hyperinsulinemic hypoglycemia vs hyperinsulinemic euglycemia
Design
Editorial
Authors
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Iatrogenic hypoglycemia may contribute to the pathogenesis of atherosclerotic vascular disease in diabetes by impairing vascular function and promoting proatherothrombotic mechanisms.
Does hyperinsulinemic hypoglycemia impair vascular function and increase proatherothrombotic mechanisms in healthy individuals?
Iatrogenic hypoglycemia may contribute to the pathogenesis of atherosclerotic vascular disease in diabetes by impairing vascular function and promoting proatherothrombotic mechanisms.
Philip E. Cryer (2015) conducted an editorial in Diabetes. Hyperinsulinemic hypoglycemia vs. Hyperinsulinemic euglycemia was evaluated on Endothelial vasodilation and vascular function. Hyperinsulinemic hypoglycemia reduced NO-mediated endothelial vasodilation and increased proatherothrombotic mechanisms compared with euglycemia in healthy individuals.
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