Key result
Male patients with disabling angina pectoris undergoing preoperative investigation had a 21% decrease in blood volume compared to predicted normal values.
Why the study?
Does blood volume deviate from predicted normal values in male patients with disabling angina pectoris undergoing preoperative investigation for coronary bypass surgery?
Observational (n=60)
Does blood volume deviate from predicted normal values in male patients with disabling angina pectoris undergoing preoperative investigation for coronary bypass surgery?
Patients with disabling angina pectoris awaiting coronary bypass surgery exhibit a significant reduction in blood volume compared to predicted normal values.
Answers are grounded in this paper and cite their sources.
Blood volume reduction may warrant preoperative consideration in disabling angina; leaves open causal role and impact on CABG outcomes.
Blood volume was measured in 60 consecutive male patients with disabling angina pectoris undergoing preoperative investigation for coronary bypass surgery. Of these patients, 58 had a lower blood volume than predicted. There was a decrease in blood volume of 21% (1.3 litres) from the predicted normal value (P less than 0.001). Seventeen per cent of the patients were on diuretics, 30% were on digitalis, and 48% were on beta-blocking drugs at the time of the study. There was no correlation between this medical treatment and the deviation in blood volume. In patients without signs of myocardial insufficiency the decrease in blood volume was most prominent, while in those with an enlarged heart and a raised left ventricular preload (at rest) the deviation was less.
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Åström et al. (1979) conducted an observational in Disabling angina pectoris (n=60). Disabling angina pectoris vs. Predicted normal blood volume was evaluated on Blood volume deviation from predicted normal value (21% decrease (1.3 litres), p=<0.001). Male patients with disabling angina pectoris undergoing preoperative investigation had a 21% decrease in blood volume compared to predicted normal values.
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