Key result
Clinical evidence of coronary artery disease did not significantly predict the frequency of thallium redistribution (45% vs 46%) in patients being considered for elective vascular procedures.
Why the study?
Does the presence of clinical indicators of coronary artery disease predict the frequency of thallium redistribution or severe CAD in patients undergoing elective vascular procedures?
Observational (n=190)
Does the presence of clinical indicators of coronary artery disease predict the frequency of thallium redistribution or severe CAD in patients undergoing elective vascular procedures?
Absolute Event Rate: 45% vs 46%
p-value: p=not significantly different
Clinical indicators of coronary disease do not reliably predict the presence of severe CAD or thallium redistribution in patients undergoing elective vascular procedures, suggesting imaging selection should be based on whether findings would alter therapy.
Clinical CAD indicators did not predict thallium redistribution; leaves open optimal preoperative imaging selection in elective vascular procedures.
We routinely performed intravenous dipyridamole thallium imaging and resting radionuclide ventriculography on 190 patients being considered for elective vascular procedures. Patients with thallium redistribution underwent coronary arteriography. Patients in group 1 (n = 78) had clinical evidence of coronary artery disease, and patients in group 2 (n = 112) had no history or electrocardiographic evidence of coronary artery disease. The frequency of thallium redistribution was not significantly different in the two groups (45% in group 1 and 46% in group 2). Coronary arteriography identified severe three-vessel or left main disease in eight patients (10%) in group 1 and 16 patients (14%) in group 2. Selection of patients for dipyridamole thallium imaging prior to vascular reconstruction should be based on whether or not documentation of the extent of coronary artery disease would influence therapy rather than on clinical indicators of coronary disease.
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Timothy F. Kresowik (1993) conducted an observational in Patients being considered for elective vascular procedures (n=190). Clinical evidence of coronary artery disease vs. No history or electrocardiographic evidence of coronary artery disease was evaluated on Frequency of thallium redistribution (p=not significantly different). Clinical evidence of coronary artery disease did not significantly predict the frequency of thallium redistribution (45% vs 46%) in patients being considered for elective vascular procedures.
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