Key result
Dipyridamole thallium imaging stratified postoperative cardiac risk, with complications occurring in 50% of patients with major redistribution changes compared to 0% of those with normal scans.
Why the study?
Does dipyridamole thallium 201 scintigraphy improve the prediction of postoperative cardiac complications compared to clinical examination in vascular surgical patients?
Cohort (n=65)
Does dipyridamole thallium 201 scintigraphy improve the prediction of postoperative cardiac complications compared to clinical examination in vascular surgical patients?
Dipyridamole thallium imaging provides valuable further risk stratification for postoperative cardiac complications in vascular surgical patients who have previous ischemic heart disease or abnormal resting ECGs.
Preoperative clinical examination, including a 12-lead resting ECG, and planar dipyridamole thallium imaging (DTI) were compared in a prospective study of 65 vascular surgical patients in regard to their value for predicting postoperative cardiac complications. Fifty-three patients underwent abdominal vascular procedures and 12 were operated on for peripheral artery disease. Thirty-six patients had ischemic heart disease (IHD) and/or abnormal findings from 12-lead resting ECG. Of these 36 patients, 11 had nonfatal cardiac complications. The remaining 29 patients were free of IHD and had normal results from ECG. No complications occurred among these 29 patients. There was no postoperative death. Thallium imaging results were abnormal in 45 patients, showing either redistribution and/or scar tissue or low washout. In 18 of these patients major changes with redistribution were present in all projections. Among these patients, 9 had a nonfatal cardiac complication. In the 27 patients with abnormalities in only one or two projections, only 2 had a cardiac event postoperatively. No cardiac complications occurred in patients with normal thallium scintigraphy findings. The patients were operated on irrespective of the results of the scans, and all recovered from any cardiac complications that occurred. In vascular surgical patients with previous IHD and/or abnormal findings from resting ECGs further risk stratification is achieved with DTI.
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Madsen et al. (1992) conducted a cohort in Vascular surgical patients (n=65). Dipyridamole thallium 201 scintigraphy vs. Clinical examination was evaluated on Postoperative cardiac complications. Dipyridamole thallium imaging stratified postoperative cardiac risk, with complications occurring in 50% of patients with major redistribution changes compared to 0% of those with normal scans.
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