Key result
Oral midazolam 7.5 mg produced greater anxiolytic effects and amnesia compared to temazepam 20 mg in 60 patients, with fewer residual post-discharge effects.
Why the study?
Does oral midazolam 7.5 mg improve anxiolysis and reduce residual post-discharge effects compared to temazepam 20 mg in patients undergoing day-stay urological surgery?
Population
60 patients undergoing day-stay urological surgery
Comparison
Midazolam 7.5 mg oral vs Temazepam 20 mg oral
Design
RCT, double-blind
Follow-up
Evening of surgery
Authors
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Supports preferring midazolam 7.5 mg over temazepam for day-stay urological premedication; extends RCT evidence on benzodiazepine selection in ambulatory surgery.
RCT (n=60)
Double-blind
Does oral midazolam 7.5 mg improve anxiolysis and reduce residual post-discharge effects compared to temazepam 20 mg in patients undergoing day-stay urological surgery?
Midazolam 7.5 mg is a more suitable oral premedicant than temazepam 20 mg for outpatient surgery due to better anxiolysis and fewer residual post-discharge effects.
Short et al. (1989) conducted an RCT in Day-stay urological surgery (n=60). Midazolam vs. Temazepam 20 mg was evaluated on Anxiolysis and sedation. Oral midazolam 7.5 mg produced greater anxiolytic effects and amnesia compared to temazepam 20 mg in 60 patients, with fewer residual post-discharge effects.
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