Key result
Hypertension causes structural changes in arteries that increase susceptibility to atherosclerosis and coronary artery disease, supporting the need for earlier treatment.
Key points are not available for this paper at this time.
Design
Review
May support earlier BP control to limit atherosclerosis; leaves open need for prospective trials to guide timing.
In this article, Freis reported that hypertension caused structural changes in arteries, which made them more susceptible to atherosclerosis (and therefore coronary artery disease). As a result of these findings, Freis argued for earlier treatment of hypertension.
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Edward D. Freis (1969) studied this question. Hypertension causes structural changes in arteries that increase susceptibility to atherosclerosis and coronary artery disease, supporting the need for earlier treatment.
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