Key result
Body weight in nonanesthetized 7- to 16-week-old pigs positively correlated with echocardiographic measurements of cardiac chamber size and functional performance.
Observational (n=90)
This study establishes normative 2-dimensional echocardiographic data for cardiac chamber size and function in nonanesthetized swine, demonstrating positive correlations with body weight.
Provides swine echocardiographic norms; leaves open translation to other species or disease models.
SUMMARY Ninety nonanesthetized 7- to 16-week-old pigs were studied, using 2-dimensional echocardiography that permits orientation of a targeted M-mode beam perpendicular to structures being studied and allows serial studies of the same cardiac regions. Normative data were obtained and included body weight and measurements of left atrial diameter, mitral valve excursion, aortic root diameter, left ventricular end-diastolic and end-systolic diameters, and left ventricular fractional shortening. A positive correlation was found between body weight and measurements of left atrial diameter, mitral valve excursion, aortic root diameter, left ventricular end-diastolic and end-syatolic diameters, and fractional shortening. A correlation was found between body weight and age. Best-fit analysis resulted in all measurements fitting either a first- or second-degree polynomial.
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Gwathmey et al. (1989) conducted an observational in Healthy (normative data) (n=90). Body weight and age was evaluated on Correlation between body weight and echocardiographic measurements (left atrial diameter, mitral valve excursion, aortic root diameter, left ventricular diameters, and fractional shortening). Body weight in nonanesthetized 7- to 16-week-old pigs positively correlated with echocardiographic measurements of cardiac chamber size and functional performance.
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