Why the study?
Does a higher dose of live attenuated varicella vaccine improve immunogenicity compared to a lower dose in healthy children?
Population
Healthy children
Comparison
Live attenuated varicella vaccine or partially… vs Partially heat-inactivated vaccine (439 pfu)
Follow-up
1 year
Authors
Loading...
Higher doses may boost immunogenicity in children; leaves open clinical protection and dosing recommendations.
Does a higher dose of live attenuated varicella vaccine improve immunogenicity compared to a lower dose in healthy children?
Higher doses of the varicella vaccine maintain better immunogenicity, suggesting efficacy is preserved until expiry despite potential degradation.
Rothstein et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: