Key result
Aging is associated with a greater prevalence of sympathetic bursts above average blood pressure and reduced sympathetic transduction via a reduced pressor response.
Observational
Aging leads to reduced sympathetic transduction, necessitating increased sympathetic outflow to maintain blood pressure.
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May explain compensatory sympathetic activation in aging; leaves open whether targeting transduction alters hypertension risk.
Bigalke et al. (2023) conducted an observational in Aging and sympathetic control of blood pressure. Aging was evaluated on Sympathetic transduction to blood pressure and prevalence of sympathetic bursts. Aging is associated with a greater prevalence of sympathetic bursts above average blood pressure and reduced sympathetic transduction via a reduced pressor response.
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