Why the study?
Does the Platelet-Activated Clotting Test (PACT) predict blood loss better than routine coagulation tests or TEG in patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
200 patients undergoing cardiac surgery with cardiopulmonary bypass
Comparison
Platelet-Activated Clotting Test vs Routine laboratory coagulation tests and…
Design
Cohort
Follow-up
4 hours post-operatively
Authors
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PACT adds no value over routine tests or TEG for post-CPB bleeding prediction; leaves open whether refined platelet assays merit prospective evaluation.
Does the Platelet-Activated Clotting Test (PACT) predict blood loss better than routine coagulation tests or TEG in patients undergoing cardiac surgery with cardiopulmonary bypass?
The Platelet-Activated Clotting Test (PACT) is not superior to thromboelastogram or routine coagulation tests for predicting excessive blood loss after cardiopulmonary bypass.
Ereth et al. (1997) studied this question.
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