Key result
Perioperative monitoring revealed that in 7 of 9 patients, postoperative bleeding was attributed to prolonged heparin anticoagulation or enhanced fibrinolysis (e.g., aPTT 47 vs. 32 seconds).
Population
49 patients selected for low bleeding risk undergoing selective primary coronary artery bypass grafting (CABG)
Design
Cohort
Follow-up
First postoperative day
Authors
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May support targeted heparin reversal or antifibrinolytics in post-CABG bleeding; hypothesis-generating for coagulation monitoring algorithms.
Observational (n=49)
PFA-100 demonstrates high specificity for adequate platelet function in uncomplicated CABG, while TEG and standard coagulation tests are useful for identifying post-bypass bleeding complications.
Hertfelder et al. (2005) conducted an observational in Coronary artery bypass grafting (n=49). Perioperative hemostatic monitoring was evaluated on Perioperative hemostatic alterations. Perioperative monitoring revealed that in 7 of 9 patients, postoperative bleeding was attributed to prolonged heparin anticoagulation or enhanced fibrinolysis (e.g., aPTT 47 vs. 32 seconds).
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