Key result
Percutaneous transluminal coronary recanalization achieved reopening in 24.4% with ISDN and 82.7% with Urokinase, and improved ejection fraction compared to conventional therapy.
Why the study?
Does percutaneous transluminal coronary recanalization improve left ventricular regional wall motion and ejection fraction in patients with acute myocardial infarction?
Population
90 patients with acute myocardial infarction within 12 hours of symptom onset
Comparison
Percutaneous transluminal coronary… vs Conventional therapy
Design
Cohort
Authors
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Early recanalization may preserve ejection fraction in acute MI; leaves open benefit versus modern therapies in randomized settings.
Cohort (n=90)
Does percutaneous transluminal coronary recanalization improve left ventricular regional wall motion and ejection fraction in patients with acute myocardial infarction?
Percutaneous transluminal coronary recanalization improves left ventricular function in acute myocardial infarction, particularly when performed within 6 hours of symptom onset.
Masakiyo Nobuyoshi (1984) conducted a cohort in Acute myocardial infarction (n=90). Percutaneous transluminal coronary recanalization (PTCR) vs. Conventional therapy was evaluated on Ejection fraction and regional wall motion shortening. Percutaneous transluminal coronary recanalization achieved reopening in 24.4% with ISDN and 82.7% with Urokinase, and improved ejection fraction compared to conventional therapy.
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