Key result
Intracoronary thrombolysis with urokinase resulted in fragmentation of an occlusive thrombus and recanalization in a patient with angiographically normal coronary arteries.
Why the study?
Does intracoronary thrombolysis with urokinase improve angiographic outcomes in a patient with inferior wall MI and normal coronary arteries?
Case Report (n=1)
Does intracoronary thrombolysis with urokinase improve angiographic outcomes in a patient with inferior wall MI and normal coronary arteries?
Intracoronary thrombolysis can successfully recanalize an occluded artery and salvage myocardium in patients with myocardial infarction and angiographically normal coronary arteries.
May support intracoronary thrombolysis in MI with normal coronaries; hypothesis-generating and requires prospective validation.
We report the case of a 50-year-old male who had classical ECG signs of inferior wall myocardial infarction. Intracoronary thrombolysis resulted in fragmentation of a thrombus in the lumen of the right coronary artery. Angiography 1 month later showed no abnormalities at the site of previous thrombus. Ergonovine stress did not produce spasm. We conclude that (1) a mild cardial infarction can occur with an occlusive thrombus arising in angiographically normal coronary arteries; (2) transient change in minimal atheromata or spasm may induce such thrombi; and (3) thrombolytic therapy may be able to expedite recanalization of the occluded artery and salvage the myocardium.
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Watabe et al. (1983) conducted a case report in Inferior wall myocardial infarction (n=1). Intracoronary thrombolysis with urokinase was evaluated on Fragmentation of thrombus and recanalization. Intracoronary thrombolysis with urokinase resulted in fragmentation of an occlusive thrombus and recanalization in a patient with angiographically normal coronary arteries.
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