January 1, 1988Japanese Circulation Journal-english EditionOpen Access

Intracoronary urokinase in acute myocardial infarction. Prevalence of total coronary occlusion during the early hours, effects on myocardial infarct size and left ventricular function, and outcome of residual coronary stenosis.

View Full Paper

Ask AI

Bookmark

Why the study?

Does intracoronary urokinase improve recanalization, infarct size, and left ventricular function in patients with acute myocardial infarction?

Population

88 acute myocardial infarction patients evaluated within 6 hours of the onset of symptoms.

Design

Cohort

Follow-up

chronic stage

Authors

TMTakeshi MotomiyaHiroshima Prefectural Rehabilitation Center YTYoshiki TokuyasuTokyo Metropolitan Hiroo Hospital KWKôji WatanabeUniversity of Miyazaki

Discussion

Member takes

Implication

Supports selective intracoronary urokinase use by occlusion type; leaves open randomized confirmation of functional benefit in total occlusion.

Structured PICO

Does intracoronary urokinase improve recanalization, infarct size, and left ventricular function in patients with acute myocardial infarction?

Population

88 acute myocardial infarction patients evaluated within 6 hours of the onset of symptoms.

Intervention

Intracoronary urokinase (intracoronary thrombolysis)

Outcome

Recanalization rate, myocardial infarct size, left ventricular function, and outcome of residual coronary stenosissurrogate

Intracoronary urokinase achieves recanalization in acute myocardial infarction, but functional benefits regarding infarct size and left ventricular function appear limited to patients with subtotal rather than total occlusion.

Cite This Study

Motomiya et al. (1988) studied this question.

synapsesocial.com/papers/6a8be845dd62e0468bc5d349 https://doi.org/10.1253/jcj.52.702

View Full Paper

Ask AI

Bookmark

Implication

Supports selective intracoronary urokinase use by occlusion type; leaves open randomized confirmation of functional benefit in total occlusion.

Intracoronary urokinase in acute myocardial infarction. Prevalence of total coronary occlusion during the early hours, effects on myocardial infarct size and left ventricular function, and outcome of residual coronary stenosis.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Intracoronary urokinase in acute myocardial infarction. Prevalence of total coronary occlusion during the early hours, effects on myocardial infarct size and left ventricular function, and outcome of residual coronary stenosis.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider