April 1, 1986Circulation

A clinicopathologic study of patients with hemorrhagic myocardial infarction treated with selective coronary thrombolysis with urokinase.

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Population

30 patients with acute myocardial infarction (AMI) undergoing autopsy

Design

Case_series

Follow-up

Up to over 17 days (interval from SICT to death)

Authors

HFHideki FujiwaraKyoto Women's University TOTomoya OnoderaEarthquake Engineering Research Institute MTMasaru TanakaKyushu University

Discussion

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Implication

Hemorrhagic infarction may occur late after SICT; hypothesis-generating case report that should not yet change practice.

Structured PICO

Population

30 patients with acute myocardial infarction (AMI) undergoing autopsy

Intervention

Selective intracoronary thrombolysis (SICT) with urokinase (240,000 to 1,200,000 U) injected into the infarct-related coronary artery at 2 to 9 hours (4 +/- 2 hours) after the onset of AMI

Outcome

Degree of hemorrhage (macroscopically and microscopically) in the infarct areasurrogate

Selective intracoronary thrombolysis with urokinase for AMI is associated with hemorrhagic infarction specifically during the late acute stage (9 hours to 11 days post-treatment).

Cite This Study

Fujiwara et al. (1986) studied this question.

synapsesocial.com/papers/6a70949c2163a0a01bc4caf7 https://doi.org/10.1161/01.cir.73.4.749

View Full Paper

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A clinicopathologic study of patients with hemorrhagic myocardial infarction treated with selective coronary thrombolysis with urokinase.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A clinicopathologic study of patients with hemorrhagic myocardial infarction treated with selective coronary thrombolysis with urokinase.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider